Hormone replacement therapy is very effective for menopause symptoms relief. Therefore when HRT was first introduced, everybody was very excited about it: patients, because HRT worked very well, doctors, because now treatment of menopause became easy.Then Women’s Health Initiative study results came out. They found that hormone replacement (HRT) increased risks of heart disease, and breast cancer. Hormones, used in WHI, were conjugated ( horse) estrogens and progestins ( not natural progesterone). The other statistics confirm these finding. For example they found that breast cancer rate in the US is declining because of cutting down on HRT. So what is the problem with traditional HRT?

The problem with synthetic or semisynthetic hormones is utilization: our body does not know what to do with them. But our body knows exactly what to do with our own hormones. Example: natural estrogen is metabolized by 2-OH pathway, which creates benign waste products. Conjugated ( horse) estrogen is metabolized by 4-OH pathway, which is not natural. The result: byproducts, linked to cancer.

Then doctors came up with the idea to use hormones chemically identical to our own hormones: method known as bioidentical hormone replacement. In fact these hormones have been on market for a long time. Example — Prometrium ( bioidentical progesterone). Estradiol and Estriol have been well known Biest. However of bioidentical hormones used in famous WHI study. Why? Because nobody wants to put money into the medications which cannot be patented. Have you seen Pepsi advertising? Many times. How about broccoli? I do not think so. Same thing with hormones.

As a physician I’m concerned with safety first. Remember: do no harm – ancient wisdom. Are bioidentical hormones safe? Do we have controlled double blind studies to confirm safety and effectiveness of the female hormones with the same molecular structure as our own? No, and we won’t have – at least in the near future. Because substances in nature, cannot be patented. Therefore no money to subsidize the studies.

Do we really need controlled studies? Effectiveness of insulin was confirmed on patient after he was injected with pancreatic extract and his blood sugar level decreased. Power of vaccination was confirmed on 21 patients only. No double blind studies. Would we get insulin or vaccines, if double blind studies were required?

Our experience and our colleges experience show, that hormones with the same molecular structures as our own are effective and safe for hormone replacement therapy, if used correctly under appropriately trained physician’s supervision. I know, that they are working for menopause and andropause. The new study, done by Aksam Yassin, MD, PhD from the Clinic of Urology and Andrology of Segeberger Clinics in Norderstedt, Germany, confirmed, that testosterone replacement therapy does not cause prostate cancer. Do we have to wait until controlled studies come out?

For more information about BHRT ( bioidentical hormone replacement therapy ) go to www.doctorkalitenko.com
Please let me know what you think about the safety of BHRT.
BHRT, HRT, hormones, safety, bioidentical hormones, bioidentical hormone replacement therapy

Technorati Tags: BHRT, HRT, hormones, safety, bioidentical hormones, bioidentical hormone replacement therapy

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This entry was posted on Monday, October 27th, 2008 at 2:05 pm and is filed under Antiaging, Bioidentical hormones, General health, Hormones. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.