There are many drugs for depression, but it is difficult to achieve not only long lasting results, but also any significant mood improvement. A recent study, published in the New England Journal of Medicine may shed some light on this problem: bias was found in reporting the efficacy of antidepressants.

Studies with positive results were almost always published, while studies with negative results had much less of a chance, and even if they were published, the results tended to be presented in positive way for the drug.

Therefore, positive impression about drugs efficacy has been created, which might not reflect the real efficacy of antidepressant drugs.

The solution of the problem might be as follows:

1.    Mood changes can be caused by hormonal levels decline, for example menopause or andropause. Therefore hormonal testing and necessary correction with hormone replacement therapy (HRT) might be helpful.
2.    Proper nutrition might be helpful to treat depression. Most antidepressants work by increasing the serotonin level in brain synapses. Our gut is the major source of endogenous serotonin. Therefore taking care of the gut by eating proper food and getting detoxification done might be very valuable.

Of course, this cannot be applied to purely psychiatric cases.

At my offices, we offer our patients appropriate hormonal testing and hormonal replacement therapy (HRT) if needed. Menopause and andropause are the major treatment targets. Various dietary solutions are also available, as well as detoxification protocols. The results of treatment are monitored because such treatments should be done under physician’s supervision only.

Tags: Andropause, Antidepressants, Hormone level, hormone replacement, Menopause, Treatment for depression

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This entry was posted on Thursday, January 24th, 2008 at 11:16 am and is filed under Do you know, General health, Hormones, Problem - Solution. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.